The Hypoxic Ischemic Encephalopathy Model of Perinatal Ischemia
نویسندگان
چکیده
منابع مشابه
The Hypoxic Ischemic Encephalopathy Model of Perinatal Ischemia
Hypoxic-Ischemic Encephalopathy (HIE) is the consequence of systemic asphyxia occurring at birth. Twenty five percent of neonates with HIE develop severe and permanent neuropsychological sequelae, including mental retardation, cerebral palsy, and epilepsy. The outcomes of HIE are devastating and permanent, making it critical to identify and develop therapeutic strategies to reduce brain injury ...
متن کاملPerinatal Hypoxic-Ischemic Encephalopathy
Perinatal hypoxic-ischemic encephalopathy (HIE) is an important cause of brain injury in the newborn and can result in long-term devastating consequences. Perinatal hypoxia is a vital cause of long-term neurologic complications varying from mild behavioural deficits to severe seizure, mental retardation, and/or cerebral palsy in the newborn. In the mammalian developing brain, ongoing research i...
متن کاملStem Cell Therapy in Hypoxic Ischemic Encephalopathy
Introduction there are one million deaths from asphyxia in newborn annually. Management of this newborn is only supportive. Autologuse stem cell therapy may reduce mortality and long term morbidity. Outcome of asphyxiated newborn is related to damage CNS cells. Stem cells prevent Apoptosis and induce repairmen of injured neurons. Methods in a review study all article related to three keyword...
متن کاملPreterm Hypoxic–Ischemic Encephalopathy
Hypoxic-ischemic encephalopathy (HIE) is a recognizable and defined clinical syndrome in term infants that results from a severe or prolonged hypoxic-ischemic episode before or during birth. However, in the preterm infant, defining hypoxic-ischemic injury (HII), its clinical course, monitoring, and outcomes remains complex. Few studies examine preterm HIE, and these are heterogeneous, with vari...
متن کاملHypoxic-Ischemic Encephalopathy Biomarkers
Background Clinical RS for HIE are intended to determine trial entry and to compare groups within or between trials. Categorical current schemes do not reflect the broad clinical continuum spectrum of HIE and they were not design for this task. Objective To prospectively validate a new structured multi-item RS for HIE. Methods A standardised structured ordinal RS for HIE with 7 clinical items (...
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ژورنال
عنوان ژورنال: Journal of Visualized Experiments
سال: 2008
ISSN: 1940-087X
DOI: 10.3791/955